Methodological Study of Vancomycin Dosing in Elderly Patients Using Actual Serum Creatinine Versus Rounded Serum Creatinine
نویسندگان
چکیده
منابع مشابه
Methodological Study of Vancomycin Dosing in Elderly Patients Using Actual Serum Creatinine Versus Rounded Serum Creatinine
PURPOSE The practice of intentional rounding up of serum creatinine (SCr) in elderly patients with low measured values can lead to an underestimation of creatinine clearance and subsequent inaccurate dosing of medications. Thus, the purpose of this study was to evaluate the accuracy of vancomycin dose calculations for patients aged ≥65 years using an SCr rounded up to 1 mg/dL versus actual SCr....
متن کاملNephrotoxicity of vancomycin in patients with normal serum creatinine.
Chronic renal disease is frequent in the general population. In the case of epidemia or pandemia of avian influenza A (H5N1), the two neuraminidase inhibitors, oseltamivir and zanamivir will therefore be used in patients with renal impairment. Although zanamivir does not necessitate any adjustment of its dosage in patients with renal failure, because it is not absorbed after oral inhalation, os...
متن کاملSerum creatinine Glomerular Effective renal Serum creatinine Glomerular Effective renal Serum creatinine Glomerular Effective renal Serum creatinine Glomerular Effective
them to "make the most of the limited time left." Parents vividly remembered the doctor's response to their distress. The doctor's ability to accept and understand the parents' grief was important in establishing trust and shaping the future relationship. Feelings of anger, guilt, and sadness are well known to be part of the process of grieving, which may begin at the time of diagnosis when the...
متن کاملA Prospective Study to Assess Vancomycin Serum Concentrations in Pediatric Patients with Current Dosing Guidelines
Concerns about increasing bacterial resistance to vancomycin, have caused the adult treatment guidelines to recommend higher trough concentrations based on the type and location of infectious disease. Although these recommendations are not specific to children, the values can be extrapolated. This prospective study was designed to evaluate efficacy of current vancomycin dosing recommendations t...
متن کاملMulti-institutional validation study of carboplatin dosing formula using adjusted serum creatinine level.
Creatinine clearance (Ccr) is widely used as a practical substitute for glomerular filtration rate (GFR) in the Calvert formula: carboplatin dose (mg) = target area under the concentration versus time curve (AUC, mg ml(-1) min) x [GFR (ml min(-1)) + 25]. However, it causes systematic overdosing when the creatinine levels are measured by an enzymatic peroxidase-antiperoxidase method (PAP-Cr). We...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Drugs in R&D
سال: 2017
ISSN: 1174-5886,1179-6901
DOI: 10.1007/s40268-017-0200-1